Keywords:-

Keywords: Pareto-Multiobjective Optimization (PMO), Mathematical Methods (MM), Biological Models (BM), Radiation Therapy (RT), Initial Tumor Clonogenes Number Population ( N0 ), Effective Tumor Population Clonogenes Number ( NEff ), Linear Quadratic Model (LQM), Integral Equation (IE), Tumor Control Probability (TCP), Biological Effective model (BED), Tumor Control Cumulative Probability (TCCP) ,Radiation Photon-Dose (RPD), Nonlinear Optimization, Radiotherapy Treatment Planning Optimization (TPO), Source-Surface Distance (SSD), Software Engineering Methods, Radiation Photon-Dose, Attenuation Exponential Factor (AEF), Nonlinear Optimization, Radiotherapy Wedge Filter (WF), Anisotropic Analytic Model (AAA), Fluence Factor (FF), Omega Factor (OF), Treatment Planning Optimization (TPO), Breast Tumor (BT), Artificial Intelligence (AI), Pareto-Multiobjective (PMO), Genetic Algorithms (GA) .

Article Content:-

Abstract

BED model (Biological Effective Dose) for Head and Neck tumors Hyperfractionation TPO was optimizedwith Pareto-Multiobjective (PMO) Genetic Algorithms (GA) software. Artificial Intelligence (AI) with GA is applied on Radiotherapy Treatment Planning Optimization (TPO). Secondly, the review of NEffective (Effective Tumor Population Clonogens Number) model optimization for breast cancer clonogens parameters determination in TPO (Treatment Planning Optimization) is got with 3D Graphical and Interior Optimization methods. Results series comprise PMO imaging process sequences and numerical values of PMO and NEffective model for Head and Neck cancer parameters. Further results demonstrate PMO-GA BED model both with Pareto-Optimal Front detailed graphics, charts and numerical dose fractionation datasets. Supplemental review of new recent applications with 3D Isodoses TPO with AAA (Anisotropic Analytic Algorithm) model wedge filters dose delivery is shown. Advanced RT Head and Neck cancer TPO, and tumors in general for Fractionation-dose protocols are explained.

References:-

References

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Casesnoves, F. (2023). Radiotherapy Genetic Algorithm Pareto-Multiobjective Optimization of Biological Efective Dose and Clonogens Models for Head and Neck Tumor Advanced Treatment. International Journal Of Mathematics And Computer Research, 11(1), 3156-3177. https://doi.org/10.47191/ijmcr/v11i1.08

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